Mechanism Underlying Initiation of Paroxysmal Atrial Flutter/Atrial Fibrillation by Ectopic Foci
نویسندگان
چکیده
منابع مشابه
Mechanism underlying initiation of paroxysmal atrial flutter/atrial fibrillation by ectopic foci: a simulation study.
BACKGROUND The mechanisms underlying paroxysmal atrial flutter/atrial fibrillation initiation by ectopic foci from various locations are unclear. METHODS AND RESULTS We used parallel computational techniques to study an anatomically accurate 3-dimensional atrial structure incorporating a detailed ionic-current model of an atrial myocyte. At the single-cell level, upregulation of the L-type Ca...
متن کاملSuppression of Paroxysmal Atrial Fibrillation by Pacing
Atrial Fibrillation (AF) affects approximately five million people worldwide. The incidence of AF increases with aging and more common in males.1 Atrial fibrillation is the most common cardiogenic cause of stroke and exacerbates heart failure. Despite the prevalence of AF, it is still one of the most difficult arrhythmia to treat.2 The management option of AF ranges from pharmacological therapy...
متن کاملCanine model of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia.
Both autonomic nerve activity and electrical remodeling are important in atrial arrhythmogenesis. Therefore, dogs with sympathetic hyperinnervation, myocardial infarction (MI), and complete atrioventricular block (CAVB) may have a high incidence of atrial arrhythmias. We studied eight dogs (experimental group) with MI, CAVB, and sympathetic hyperinnervation induced either by nerve growth factor...
متن کامل[The superior vena cava as a site of ectopic foci in atrial fibrillation].
Radiofrequency catheter ablation of ectopic foci that trigger atrial fibrillation has been established as a curative method for patients with symptomatic paroxysmal atrial fibrillation. Although the majority of these foci are located in and around the pulmonary veins, other less common locations have been identified. Recognition that foci can lie outside the pulmonary veins is important for ens...
متن کاملOnset mechanism of paroxysmal atrial fibrillation detected by ambulatory Holter monitoring.
AIMS The aim of this study was to evaluate the mechanisms of induction of paroxysmal atrial fibrillation (PAF) by analysis of its onset recorded on Holter monitoring (HM). METHODS AND RESULTS One hundred and seven HM were evaluated in 90 patients (mean age 67.7, cardiac disease in 31.1%), with one or more self-terminating episodes of PAF, lasting >or=30 s. Two hundred and thirty-three episode...
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ژورنال
عنوان ژورنال: Circulation
سال: 2007
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.106.656504